Radcliffe Camera, Oxford
OXFORD · 51.7548°N 1.2544°W
OxRML/Reasoning with Machines Lab
Active 2026/Open to collaborations
About the lab

Reasoning with Machines Lab

@ Oxford University

Led by Prof. Adam Mahdi, our lab advances the science of AI evaluation, benchmarking, safety and security. Through rigorous empirical research, we study how LLMs and agentic systems reason, interact with humans and drive scientific discovery.

Mission

We advance the science of AI evaluation, safety, and reasoning through rigorous empirical research, in the open and over the long term.

10
Featured papers since 2024
15
Researchers in the lab
06
Top venues this year
01
Nature Medicine, Feb 2026
§ 02 · Research Themes

Four research themes the lab works across.

Four areas of focused work: AI evaluation, AI safety and security, agentic AI for science, and human–AI interaction.

Theme 01

Evaluation

Benchmarks and Evaluation

We develop the science of LLM evaluation, setting the standard for rigorous assessment and identifying hidden risks before they matter.

Focus

How benchmarks are built, what they claim to measure, and what they actually capture.

In active practice

Theme 02

Safety

AI Safety and Security

From bias and toxicity to agentic misalignment, we study the full spectrum of AI risk and develop the technical and governance tools to address it.

Focus

The full spectrum of AI risk — bias, toxicity, agentic misalignment — studied at the neuron and at deployment.

In active practice

Theme 03

Agentic

Agentic AI for Science

We build agentic systems that automate scientific knowledge synthesis and discovery, with a focus on agents that are reliable, transparent and domain-grounded.

Focus

Agentic systems that synthesise scientific knowledge reliably enough to act on.

In active practice

Theme 04

Human-AI

Human–AI Interaction

We run large-scale empirical studies on how people use AI for high stakes decisions, from healthcare and law to policy and beyond.

Focus

How people use AI in high-stakes decisions — healthcare, law, policy — studied empirically.

In active practice

Each theme runs on a multi-year horizon and feeds the others.

§ 03 · Publications

Ten recent papers from the lab.

Recent peer-reviewed work across evaluation, safety, agentic AI, and human–AI interaction. The most recent paper sits at the top.

No.PaperVenue · Date
  1. No. 02

    A Positive Case for Faithfulness: LLM Self-Explanations Help Predict Model Behavior

    A positive result on LLM self-explanation faithfulness, usable as a behavioural predictor when the measurement is set up right.

    H Mayne, JS Kang, D Gould, K Ramchandran, A Mahdi, NY Siegel

    AI Safety and AlignmentBenchmarks and Evaluation

    ICML

    May 2026

  2. No. 03

    It's a TRAP! Task-Redirecting Agent Persuasion Benchmark for Web Agents

    A web-agent benchmark for resistance to social engineering. Frontier agents fall for the persuasion attack.

    K Korgul, Y Yang, A Drohomirecki, P Błaszczyk, W Howard, L Aichberger, C Russell, P H S Torr, A Mahdi, A Bibi

    Benchmarks and EvaluationAgentic AIAI Safety and Alignment

    ICML

    May 2025

  3. No. 04

    Reliability of LLMs as medical assistants for the general public: a randomized preregistered study

    A preregistered, randomised Nature Medicine study on the public’s use of LLMs as medical assistants.

    AM Bean, RE Payne, G Parsons, HR Kirk, J Ciro, R Mosquera-Gómez, S Hincapié, AS Ekanayaka, L Tarassenko, L Rocher, A Mahdi

    AI in HealthcareBenchmarks and Evaluation

    Nature Medicine

    February 2026

  4. No. 05

    Measuring what matters: Construct validity in large language model benchmarks

    A construct-validity audit of the benchmarks the field treats as ground truth.

    AM Bean, RO Kearns, A Romanou, FS Hafner, H Mayne, J Batzner, et al.

    Benchmarks and Evaluation

    NeurIPS Datasets and Benchmarks

    November 2025

  5. No. 06

    Evaluating LLM-as-a-Judge under Multilingual, Multimodal and Multi-domain Constraints

    How LLM-as-a-judge degrades, sometimes catastrophically, across language, modality, and domain.

    S Padarha, E Semenova, B Vidgen, A Mahdi, S A Hale

    Benchmarks and EvaluationAI Safety and Alignment

    NeurIPS LLM Lifecycle Workshop

    November 2025

  6. No. 07

    How Does DPO Reduce Toxicity? A Mechanistic Neuron-Level Analysis

    A neuron-level account of how Direct Preference Optimization reduces toxicity.

    Y Yang, F Sondej, H Mayne, A Lee, A Mahdi

    AI Safety and Alignment

    EMNLP

    November 2025

  7. No. 08

    LLMs Don't Know Their Own Decision Boundaries: The Unreliability of Self-Generated Counterfactual Explanations

    Counterfactual self-explanations are fluent but systematically mis-locate the model's decision boundary.

    H Mayne, RO Kearns, Y Yang, AM Bean, E Delaney, C Russell, A Mahdi

    AI Safety and AlignmentBenchmarks and Evaluation

    EMNLP

    September 2025

  8. No. 09

    Review of multimodal machine learning approaches in healthcare

    A survey mapping the multimodal healthcare ML landscape: fusion strategies, deployment realities.

    F Krones, U Marikkar, G Parsons, A Szmul, A Mahdi

    AI in Healthcare

    Information Fusion

    February 2025

  9. No. 10

    LingOly-TOO: Disentangling Reasoning from Knowledge with Templatised Orthographic Obfuscation

    A reasoning benchmark that disentangles inference from memorisation by templatised orthographic obfuscation.

    J Khouja, K Korgul, S Hellsten, L Yang, V Neacsu, H Mayne, RO Kearns, A Bean, A Mahdi

    Benchmarks and Evaluation

    ICLR

    April 2026

10 papers · most recent first

§ 04 · Team

The researchers of the lab.

DPhil and MSc students, fellows, and affiliates. Each is introduced by what they are currently working on and what they are working toward.

Prof. Adam Mahdi

Principal Investigator

Prof. Adam Mahdi

Oxford Internet Institute, University of Oxford

Adam leads OxRML. The group studies how language models reason, how people work with them, and how agentic systems behave on real scientific and decision-making tasks.

Currently

Leading the lab’s research across evaluation, safety, agentic AI, and human–AI interaction.

Working toward

Advancing AI evaluation as a rigorous science, with the same care as the systems it studies.

Felix Krones

No. 01

Felix Krones

DPhil Student

Currently

Multimodal evaluation across imaging and clinical text.

Toward

Digital-health systems measured before they are deployed.

Djavan De Clercq

No. 02

Djavan De Clercq

DPhil Student

Currently

LLMs applied to food-security data and policy questions.

Toward

Decision tools for food systems that hold up under audit.

Andrew M. Bean

No. 03

Andrew M. Bean

DPhil Student

Currently

LLM evals that capture how people use models in practice.

Toward

A standard for evaluating LLMs in real human contexts of use.

Yushi Yang

No. 04

Yushi Yang

DPhil Student

Currently

Post-training for LLM and agentic alignment, at the neuron level.

Toward

Alignment interventions whose mechanism we can explain.

Harry Mayne

No. 05

Harry Mayne

DPhil Student

Currently

Interpretability and safety-relevant LLM evaluations.

Toward

Interpretability methods that practitioners can trust under shift.

Jessica Rodrigues

No. 06

Jessica Rodrigues

DPhil Student

Currently

Knowledge graphs for metascience and research synthesis.

Toward

Synthesis tools scientists treat as collaborators, not search engines.

Guy Parsons

No. 07

Guy Parsons

DPhil Student

Currently

Healthcare AI evaluation grounded in clinical workflow.

Toward

Digital-health products that earn the trust of clinicians and patients.

Karolina Korgul

No. 08

Karolina Korgul

DPhil Student

Currently

Agentic-AI safety, including web-agent persuasion attacks.

Toward

Web agents that resist social engineering as a default behaviour.

Ryan Othniel Kearns

No. 09

Ryan Othniel Kearns

DPhil Student

Currently

The science of evals: measuring reasoning honestly.

Toward

A field where every benchmark publishes its construct validity.

Shreyansh Padarha

No. 10

Shreyansh Padarha

DPhil Student

Currently

Agentic systems for science, with safety and eval rigour.

Toward

Scientific agents auditable enough to act on in real research.

Mia Kussman

No. 11

Mia Kussman

MSc Student

Currently

Studies of human–LLM interaction and LLM evaluation.

Toward

Interaction patterns that improve, rather than substitute, human judgement.

Caleb Tan

No. 12

Caleb Tan

MSc Student

Currently

LLM evaluation and reasoning benchmarks.

Toward

Reasoning evals that separate genuine inference from recall.

Sebastian Petric

No. 13

Sebastian Petric

Visiting Policy Fellow

Currently

LLMs applied to financial time series, at the policy boundary.

Toward

Honest characterisation of LLM utility in high-stakes financial settings.

Tristan Naidoo

No. 14

Tristan Naidoo

Research Affiliate

Currently

Public-health AI and LLM evaluations grounded in epidemiology.

Toward

Public-health AI evaluated like a health intervention.

Josh Lawman

No. 15

Josh Lawman

Entrepreneur in Residence

Currently

Research-to-product translation

Toward

Steady work on research-to-product translation.

§ 05 · News

Recent news from the lab.

Papers accepted, conferences attended, and awards received. Most recent first.

DateEntryCategory
  1. May 2026

    Papers accepted at ICML 2026!

    Paper
  2. April 2026

    OxRML at ICLR 2026

    Conference
  3. February 2026

    Ryan Othniel Kearns Wins MSc Thesis Prize

    Award
  4. February 2026

    New Paper in Nature Medicine!

    Paper
  5. December 2025

    OxRML @ NeurIPS 2025

    Conference
  6. November 2025

    OxRML @ EMNLP 2025

    Conference
  7. June 2025

    Prof. Adam Mahdi Wins Teaching Excellence Award 2025

    Award
  8. February 2025

    New Paper in Information Fusion!

    Paper
  9. December 2024

    OxRML @ NeurIPS 2024

    Conference
  10. September 2024

    Winners of 2024 PhysioNet Challenge

    Award
  11. July 2024

    OxRML @ ICML 2024

    Conference

11 entries · most recent first

§ 06 · Engage with the Lab

Three ways to work with the lab — long-term, and on shared standards.

Three formats for partnering with the lab. Each is a real commitment — we are selective about partners and ramp slowly, because shared roadmaps need shared standards.

Format · 01

Workshops for industry teams

On-site sessions for product and ML teams on evaluation, safety, and agent reliability.

Half-day to multi-week formats. For teams shipping LLM products in healthcare, finance, retail, and government.

Cadence
Half-day to multi-week
Format
On-site sessions for product and ML teams
What we commit
We bring the eval and safety toolkit we use in the lab and adapt it to the team in the room.
Book a workshop

Format · 02

Tools co-built with engineering partners

We work with engineering partners to turn lab work into tools other teams can run.

Evaluation harnesses, safety dashboards, agentic-research platforms. We build them with partners we trust, carrying the research methods through to the code.

Cadence
Quarterly cycles
Format
Joint roadmaps with first-class development studios
What we commit
Lab breakthroughs become production tools: eval harnesses, safety dashboards, agentic-research platforms.
See our builds

Format · 03

Research partnerships

Applied research collaborations with foundations, governments, and large companies.

Multi-year programmes: shared roadmaps, sponsored DPhil studentships, named labs.

Cadence
Multi-year, named
Format
Foundations, governments, global corporates
What we commit
Named labs, dedicated DPhil studentships, shared scientific direction. We work with partners who care about getting it right.
Start a conversation

We work with foundations, governments, and companies who want AI evaluation, safety, and reasoning treated as a science.

Read our research

We reply to every serious enquiry.

§ 07 · Venues

Where the work has been published.

Universities, journals, and conferences where the lab’s work has been hosted, peer-reviewed, and published.

  • 01University of OxfordHost institution
  • 02Oxford Internet InstituteAffiliated department
  • 03Nature MedicinePublished 2026
  • 04ICMLSpotlight & papers, 2026
  • 05NeurIPSDatasets & Benchmarks, 2025
  • 06ICLRAccepted, 2026
  • 07EMNLPMultiple, 2025

§ 08 · AI News

From the OxRML lab.

New papers, open positions, partnership opportunities, and what we have been reading.

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